Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption

Despite many antihypertensive options, uncontrolled hypertension remains pervasive. Aldosterone synthase inhibitors show robust blood pressure reductions and have the potential to reshape hypertension treatment, though cost and access may impact broad adoption.

Authors

Institutions

Publication Details

Journal
PLoS Medicine
Published
2026-02-09
DOI
https://doi.org/10.1371/journal.pmed.1004900
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption

Luke J. Laffin, Steven E. Nissen
PLoS Medicine
Hormonal Regulation and Hypertension
article

Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption

Luke J. Laffin, Steven E. Nissen
article en

Abstract

Despite many antihypertensive options, uncontrolled hypertension remains pervasive. Aldosterone synthase inhibitors show robust blood pressure reductions and have the potential to reshape hypertension treatment, though cost and access may impact broad adoption.

PLoS MedicineVol. 23(2)
Cleveland Clinic (US), Cleveland Foundation (US)
Good health and well-being
Openalex Percentile: Top 64%
Hormonal Regulation and Hypertension
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption — Luke J. Laffin, Steven E. Nissen · PLoS Medicine (2026) | TGRS Research Map | TGRS