Association between serum PLP levels and the natural resolution of nausea and vomiting in pregnancy: a secondary analysis

Higher serum PLP levels in early pregnancy were significantly associated with a faster rate of spontaneous remission of NVP. The observed linear association suggests that the active form of vitamin B6 may regulate NVP progression, reflecting the biochemical basis of natural symptom resolution. PLP may be a potential biomarker for evaluating NVP severity and predicting individualized therapeutic response.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-02-09
DOI
https://doi.org/10.3389/fnut.2026.1745093
Primary Topic
Pregnancy and Medication Impact
Type
article
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article

Association between serum PLP levels and the natural resolution of nausea and vomiting in pregnancy: a secondary analysis

Baichao Shi, Jingshu Gao, Jing Cong, Jiaxing Feng et al.
Frontiers in Nutrition
Pregnancy and Medication Impact
article

Association between serum PLP levels and the natural resolution of nausea and vomiting in pregnancy: a secondary analysis

Baichao Shi, Jingshu Gao, Jing Cong, Jiaxing Feng, Fengjuan Lu, Jiannan Yu, xiaoke Wu, Zhuwei Gao, Hong Yu, Zihan Li, Yu Yao
article en

Abstract

Higher serum PLP levels in early pregnancy were significantly associated with a faster rate of spontaneous remission of NVP. The observed linear association suggests that the active form of vitamin B6 may regulate NVP progression, reflecting the biochemical basis of natural symptom resolution. PLP may be a potential biomarker for evaluating NVP severity and predicting individualized therapeutic response.

Frontiers in NutritionVol. 13
Zhejiang Chinese Medical University (CN), Heilongjiang University of Chinese Medicine (CN), First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 64%
Pregnancy and Medication Impact
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