Modeling the effect of alcohol consumption on the progression dynamics of Hepatitis C infection with treatment
This research introduces a model that integrates a logistic approach to alcohol consumption to delve into the effect of alcohol consumption on the advancement of hepatitis C infection, evaluates the effects of addressing hepatitis C treatment and reducing alcohol consumption to minimal levels in the control of hepatitis C infection. The hepatitis C model was well established and biologically reasonable, indicating that all model solutions were non-negative and associated with non-negative initial conditions. Stability analysis revealed that the disease-free and endemic equilibrium points were locally and globally asymptotically stable whenever the basic reproduction number, [Formula: see text] and [Formula: see text] respectively. Sensitivity and numerical analysis of the model showed that improving treatment for individuals with chronic infection, along with reducing alcohol consumption, led to a notable decrease in the number of people affected by chronic infection.
Authors
- Martin Karuhanga (ORCID: https://orcid.org/0000-0002-7254-9073)
- Michael Byamukama (ORCID: https://orcid.org/0000-0002-1357-4797)
- Agnes Mbeine Asiimwe
Institutions
- Mbarara University of Science and Technology (UG)
Publication Details
- Journal
- Mathematics in Medical and Life Sciences
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1080/29937574.2026.2620745
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00