Sarcoidosis relapse risk factors: a single-centre retrospective cluster analysis
Distinct sarcoidosis phenotypes influence recurrence risk, underscoring the need for personalised management. While Cluster 1 may achieve remission with minimal therapy, Clusters 0 and 2 highlight smoking, obesity and advanced disease as recurrence drivers. Targeted interventions, including smoking cessation, weight management and early steroid-sparing therapy, could improve long-term outcomes and reduce disease burden.
Authors
- Paola Putignano
- Francesco Rocco Bertuccio (ORCID: https://orcid.org/0009-0009-7699-6610)
- G. Stella
- Marianna Russo (ORCID: https://orcid.org/0000-0002-1476-6141)
- Davide Piloni (ORCID: https://orcid.org/0000-0002-7275-4229)
- Fady Tousa
- Mariachiara Crescenzi
- Ida Maragò
- Angelo Guido Corsico
Institutions
- University of Pavia (IT)
- Azienda Ospedaliera Ospedale Maggiore (IT)
- Policlinico San Matteo Fondazione (IT)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1136/bmjresp-2025-003495
- Primary Topic
- Sarcoidosis and Beryllium Toxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00