Cannabis Use Disorder Is Associated With Increased Risk of Acute Myocardial Infarction in Adults With Metabolic Dysfunction-Associated Steatohepatitis (MASH) Cirrhosis: A Population-Based Analysis

Among hospitalized adults with MASH cirrhosis, CUD was associated with a higher risk of acute MI but not with increased in-hospital mortality or overall major adverse cardiovascular events. These findings underscore the importance of cardiovascular risk assessment and CUD identification in this population. As this was an observational cross-sectional study, the findings represent associations and do not establish causality.

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Publication Details

Journal
Cureus
Published
2026-02-09
DOI
https://doi.org/10.7759/cureus.103299
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cannabis Use Disorder Is Associated With Increased Risk of Acute Myocardial Infarction in Adults With Metabolic Dysfunction-Associated Steatohepatitis (MASH) Cirrhosis: A Population-Based Analysis

Christian Akem Dimala, Derek Ugwendum, Nso Nso, Ifeoma Kwentoh et al.
Cureus
Cannabis and Cannabinoid Research
article

Cannabis Use Disorder Is Associated With Increased Risk of Acute Myocardial Infarction in Adults With Metabolic Dysfunction-Associated Steatohepatitis (MASH) Cirrhosis: A Population-Based Analysis

Christian Akem Dimala, Derek Ugwendum, Nso Nso, Ifeoma Kwentoh, Chukwunonso Ezeani, Lea-Pearl N. Njei, Sabastian Forsah, Sarpong Boateng, Yazan A Al-Ajlouni, Basile Njei, Prince Ameyaw, Jonathan A Dranoff, Joseph K Lim
article en

Abstract

Among hospitalized adults with MASH cirrhosis, CUD was associated with a higher risk of acute MI but not with increased in-hospital mortality or overall major adverse cardiovascular events. These findings underscore the importance of cardiovascular risk assessment and CUD identification in this population. As this was an observational cross-sectional study, the findings represent associations and do not establish causality.

CureusVol. 18(2)
University of Maryland, Baltimore (US), Montefiore Medical Center (US), Euclid University (GM), Richmond University Medical Center (US), Bridgeport Hospital (US), Harlem Hospital Center (US), Yale University (US), Osteopathic Heritage Foundation (US), Baton Rouge General (US), Ohio University (US), Yale New Haven Health System (US), The University of Texas Medical Branch at Galveston (US), University of Baltimore (US), University of Cumbria (GB), Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 62%
Cannabis and Cannabinoid Research
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Cannabis Use Disorder Is Associated With Increased Risk of Acute Myocardial Infarction in Adults With Metabolic Dysfunction-Associated Steatohepatitis (MASH) Cirrhosis: A Population-Based Analysis — Christian Akem Dimala, Derek Ugwendum, et al. · Cureus (2026) | TGRS Research Map | TGRS