Metagenomics and metabolomics integrated to explore the protective mechanisms of Mongolian medicine Zadi-5 in myocardial ischemic model rats
Zadi-5 exerts cardioprotective effects in MI rats by improving dysbiosis of the gut microbiota and regulating the glutamate-glutamine metabolism pathway. This may represent only one of the complicated protective mechanisms of Zadi-5 against MI. The cardioprotective mechanisms of Zadi-5 will be explored at the molecular and cellular levels.
Authors
- Riga Wu
- Rilebagen Hu
- Wen Zu
- Si Su (ORCID: https://orcid.org/0009-0004-1972-433X)
- A Ruhan
- Lisi Wei
- Hua Li (ORCID: https://orcid.org/0000-0003-0614-5799)
- A Tengarile
- Nirile E
- Li Li
- Rihan Wu
Institutions
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fmicb.2025.1677322
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Inner Mongolia Medical University
- National Natural Science Foundation of China
- Natural Science Foundation of Inner Mongolia