Fosfomycin at sub-minimum inhibitory concentration impairs biofilm and efflux pump activity in multidrug-resistant Klebsiella pneumoniae isolates
Fosfomycin at sub-inhibitory levels is able to disrupt biofilm architecture and the efflux pump activity in MDR K. pneumoniae, pointing to its possible role as an adjunct agent in combating antibiotic resistance.
Authors
- Maisra Mohammed El-Bouseary (ORCID: https://orcid.org/0000-0001-6503-0719)
- Fatma Sonbol
- Marwa W. Moustafa
- Tarek E. El-Banna
Institutions
- Tanta University (EG)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1186/s12866-026-04720-6
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00