Tenecteplase versus Alteplase as Bridging Thrombolysis before Mechanical Thrombectomy for Medium and Distal Vessel Occlusions
In MDVO, tenecteplase yielded comparable safety and functional outcomes to alteplase, without statistically significant differences in early or final reperfusion. In light of recent trials questioning the benefit of MT in MDVO, these data <b>suggest comparable safety and functional outcomes between tenecteplase and alteplase as bridging thrombolysis prior to mechanical thrombectomy</b>, within the limits of this observational study.
Authors
- E. Kalsoum (ORCID: https://orcid.org/0000-0002-7030-0514)
- Nicolas Chausson (ORCID: https://orcid.org/0000-0002-3512-1385)
- M Piotin
- Luca Scarcia
- Pierre Seners
- Sonia Alamowitch
- Frédéric Clarençon
- Gaspard Gerschenfeld
- Stéphane Olindo
- Julien Allard
- Fernando Pico
- Jildaz Caroff
Institutions
- Inserm (FR)
- Université Paris-Saclay (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpitaux Universitaires Henri-Mondor (FR)
- Nova : inNOvation in NeuroVAscular diseases (FR)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3174/ajnr.a9219
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00