Pittsburgh compound B positron emission tomography detects cardiomyopathy in hereditary transthyretin amyloidosis patients with negative bone scintigraphy: a pilot study

[<sup>11</sup>C]PiB PET could be an effective tool for detecting ATTR cardiomyopathy in patients with <i>TTR</i> variants associated with reduced bone scintigraphy sensitivity. However, its utility for detecting brain involvement in symptomatic hereditary ATTR patients remains uncertain.

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Publication Details

Journal
Frontiers in Nuclear Medicine
Published
2026-02-09
DOI
https://doi.org/10.3389/fnume.2026.1747625
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Pittsburgh compound B positron emission tomography detects cardiomyopathy in hereditary transthyretin amyloidosis patients with negative bone scintigraphy: a pilot study

Paul Van Snick, Gilles N. Stormezand, Bouke P. C. Hazenberg, Y. Hu et al.
Frontiers in Nuclear Medicine
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Pittsburgh compound B positron emission tomography detects cardiomyopathy in hereditary transthyretin amyloidosis patients with negative bone scintigraphy: a pilot study

Paul Van Snick, Gilles N. Stormezand, Bouke P. C. Hazenberg, Y. Hu, Paul A. van der Zwaag, G. Luurtsema, Hans L A Nienhuis, Hendrea S A Tingen, P Van Der Meer, Marish Oerlemans, Riemer H. J. A. Slart
article en

Abstract

[<sup>11</sup>C]PiB PET could be an effective tool for detecting ATTR cardiomyopathy in patients with <i>TTR</i> variants associated with reduced bone scintigraphy sensitivity. However, its utility for detecting brain involvement in symptomatic hereditary ATTR patients remains uncertain.

Frontiers in Nuclear MedicineVol. 6
University Medical Center Groningen (NL), University Medical Center Utrecht (NL), ERN GUARD-Heart (NL), University of Twente (NL)
Openalex Percentile: Top 63%
Amyloidosis: Diagnosis, Treatment, Outcomes
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Pittsburgh compound B positron emission tomography detects cardiomyopathy in hereditary transthyretin amyloidosis patients with negative bone scintigraphy: a pilot study — Paul Van Snick, Gilles N. Stormezand, et al. · Frontiers in Nuclear Medicine (2026) | TGRS Research Map | TGRS