Protocol for Factors Influencing Burnout and Its Impact on Nurse Retention in the Selected District Hospital, Eastern Cape

Burnout among nurses remains a major challenge in South Africa's public healthcare system, particularly in district hospitals where high workloads, staff shortages, and limited resources are common. In the Eastern Cape, the demands of rural healthcare further exacerbate stress, leading to emotional exhaustion, reduced professional accomplishment, and high turnover rates. This study aims to investigate the factors influencing burnout and its impact on nurse retention at St. Elizabeth Hospital in the Eastern Cape. A quantitative, cross-sectional design will be employed using stratified random sampling, with hospital departments serving as strata. A total of 209 nurses will be selected using Slovin's formula. Data will be collected through a structured questionnaire incorporating the Burnout Assessment Tool, Maslach Burnout Inventory, Personal Accomplishment Subscale, and a Burnout Knowledge and Response Survey. Descriptive statistics will summarize demographic and burnout characteristics, while chi-square tests, <i>t</i>-tests/ANOVA, Pearson correlation, and multiple regression analyses will identify associations and predictors. The study will generate evidence-based insights to guide the development of targeted interventions, including workload redistribution, enhanced managerial support, and wellness initiatives. Ultimately, improving nurse retention will enhance workforce stability, promote staff well-being, and strengthen the quality of patient care in Eastern Cape district hospitals.