Clinical Efficacy and Mechanisms of Microneedling Alone or Combined With Drugs in the Treatment of Androgenetic Alopecia

Microneedling exerts therapeutic effects by regulating hair growth signaling pathways and promoting transdermal drug delivery. It is effective for mild AGA when used alone, and achieves more significant efficacy in moderate to severe AGA when combined with drugs, with high safety. Thus, it is worthy of clinical promotion. However, this study has limitations such as a small sample size and male-only participants, and further multi-center, large-sample RCTs are needed for validation.

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Publication Details

Journal
Journal of Cosmetic Dermatology
Published
2026-02-01
DOI
https://doi.org/10.1111/jocd.70726
Primary Topic
Hair Growth and Disorders
Type
article
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article

Clinical Efficacy and Mechanisms of Microneedling Alone or Combined With Drugs in the Treatment of Androgenetic Alopecia

B. Zhang, Gao Jian, Jianying Shangguan, Suiyi Liu et al.
Journal of Cosmetic Dermatology
Hair Growth and Disorders
article

Clinical Efficacy and Mechanisms of Microneedling Alone or Combined With Drugs in the Treatment of Androgenetic Alopecia

B. Zhang, Gao Jian, Jianying Shangguan, Suiyi Liu, Yafei Huang, Guorui Li, Yaping Zhang, Yongyong Zhang, Jujing Liang, Lanlan Ma, Junjun Geng
article en

Abstract

Microneedling exerts therapeutic effects by regulating hair growth signaling pathways and promoting transdermal drug delivery. It is effective for mild AGA when used alone, and achieves more significant efficacy in moderate to severe AGA when combined with drugs, with high safety. Thus, it is worthy of clinical promotion. However, this study has limitations such as a small sample size and male-only participants, and further multi-center, large-sample RCTs are needed for validation.

Journal of Cosmetic DermatologyVol. 25(2)
Jiuquan Iron & Steel (China) (CN)
Good health and well-being
Openalex Percentile: Top 64%
Hair Growth and Disorders
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