Endometrial aging and uterine receptivity: endometrial receptivity analysis (ERA) outcomes in female patients of diverse age groups

Uterine age was not associated with increased odds of non-receptive ERA, suggesting that the test does not capture age-related changes in endometrial receptivity. Although endometrial aging is implicated in reduced embryo transfer success, the ERA should not be ordered solely on the basis of uterine age. The ERA may not reliably detect age-related endometrial differences in the window of implantation at a clinical level.

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Publication Details

Journal
Journal of Assisted Reproduction and Genetics
Published
2026-02-09
DOI
https://doi.org/10.1007/s10815-026-03824-2
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Endometrial aging and uterine receptivity: endometrial receptivity analysis (ERA) outcomes in female patients of diverse age groups

D. Huang, Hakan Cakmak, Meagan Chan, Kaia M. Schwartz et al.
Journal of Assisted Reproduction and Genetics
Ovarian function and disorders
article

Endometrial aging and uterine receptivity: endometrial receptivity analysis (ERA) outcomes in female patients of diverse age groups

D. Huang, Hakan Cakmak, Meagan Chan, Kaia M. Schwartz, Bahar D. Yilmaz
article en

Abstract

Uterine age was not associated with increased odds of non-receptive ERA, suggesting that the test does not capture age-related changes in endometrial receptivity. Although endometrial aging is implicated in reduced embryo transfer success, the ERA should not be ordered solely on the basis of uterine age. The ERA may not reliably detect age-related endometrial differences in the window of implantation at a clinical level.

Journal of Assisted Reproduction and Genetics
Reproductive Science Center (US)
National Institutes of Health
Gender equality
Openalex Percentile: Top 63%
Ovarian function and disorders
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