Combination of amyotrophic lateral sclerosis with Alzheimer’s disease

The combination of amyotrophic lateral sclerosis (ALS) with Alzheimer's disease is rare. Currently, it is unclear whether such comorbidity is an accidental coincidence or a manifestation of a specific pathological process. A case of simultaneous occurrence of classic symptoms of the bulbar form of ALS and Alzheimer's disease is presented. The possible mechanisms of the combination of two diseases are analyzed.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2026-02-09
DOI
https://doi.org/10.17116/jnevro2026126011132
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
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Combination of amyotrophic lateral sclerosis with Alzheimer’s disease

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Combination of amyotrophic lateral sclerosis with Alzheimer’s disease

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article en

Abstract

The combination of amyotrophic lateral sclerosis (ALS) with Alzheimer's disease is rare. Currently, it is unclear whether such comorbidity is an accidental coincidence or a manifestation of a specific pathological process. A case of simultaneous occurrence of classic symptoms of the bulbar form of ALS and Alzheimer's disease is presented. The possible mechanisms of the combination of two diseases are analyzed.

S S Korsakov Journal of Neurology and PsychiatryVol. 126(1)
Pirogov Russian National Research Medical University (RU), Bashkir State Medical University (RU)
Good health and well-being
Openalex Percentile: Top 64%
Amyotrophic Lateral Sclerosis Research
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