Crosstalk between ZEB1 expression and CD163+ Tumor-Associated Macrophages in Muscle-Invasive Urothelial Carcinoma
Elevated ZEB1 expression is strongly associated with poor prognosis in BC and closely correlated with an increased density of CD163+TAMs, further contributing to adverse outcomes. These findings highlight the potential of ZEB1 as a prognostic biomarker and underscore the therapeutic relevance of targeting TAMs in the management of BC.
Authors
- Fatma M M Kamal
- Sara Salah Abdel-Hakeem
Institutions
- Assiut University (EG)
Publication Details
- Journal
- Asian Pacific Journal of Cancer Prevention
- Published
- 2026-02-01
- DOI
- https://doi.org/10.31557/apjcp.2026.27.2.499
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00