Switching patients with PNH from pegcetacoplan to iptacopan: a case series
In this case series, three patients with PNH were successfully transitioned from pegcetacoplan to iptacopan monotherapy. No patients exhibited laboratory evidence of BTH, EVH, or intravascular hemolysis after switching to iptacopan.
Authors
- Srinivasa Reddy Sanikommu (ORCID: https://orcid.org/0000-0002-9681-0483)
- Carmelo Gurnari (ORCID: https://orcid.org/0000-0001-6829-5544)
- Mark Orland (ORCID: https://orcid.org/0000-0002-1842-6187)
- J Maciejewski
- David Dingli
Institutions
- University of Rome Tor Vergata (IT)
- Cleveland Clinic (US)
- Levine Cancer Institute (US)
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Hematology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1080/16078454.2026.2618403
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00