Outcomes comparison between novel hydroxyapatite enhanced polyetheretherketone and titanium implants after anterior lumbar interbody fusion

Surface-enhanced PEEK and titanium ALIF implants demonstrated high fusion rates, low rates of subsidence and reoperation, and clinically meaningful improvements in disability and back pain at 12 months. These results suggest that modern surface-enhanced interbody implants may mitigate the historical nonunion risk of untreated PEEK and subsidence risk of untreated titanium, allowing implant selection to be guided by surgeon preference and case-specific factors rather than performance.

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Publication Details

Journal
Journal of Spine Surgery
Published
2026-02-01
DOI
https://doi.org/10.21037/jss-25-115
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
Field-Weighted Citation Impact
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article

Outcomes comparison between novel hydroxyapatite enhanced polyetheretherketone and titanium implants after anterior lumbar interbody fusion

Yusuf Rafiqzad, Ehsan Jazini, Wondwossen T. Lerebo, Colin M. Haines et al.
Journal of Spine Surgery
Spine and Intervertebral Disc Pathology
article

Outcomes comparison between novel hydroxyapatite enhanced polyetheretherketone and titanium implants after anterior lumbar interbody fusion

Yusuf Rafiqzad, Ehsan Jazini, Wondwossen T. Lerebo, Colin M. Haines, Lindsay D. Orosz, Peter G. Passias, Rita T. Roy
article en

Abstract

Surface-enhanced PEEK and titanium ALIF implants demonstrated high fusion rates, low rates of subsidence and reoperation, and clinically meaningful improvements in disability and back pain at 12 months. These results suggest that modern surface-enhanced interbody implants may mitigate the historical nonunion risk of untreated PEEK and subsidence risk of untreated titanium, allowing implant selection to be guided by surgeon preference and case-specific factors rather than performance.

Journal of Spine SurgeryVol. 12(2)
Duke Medical Center (US), Virginia Spine Institute (US)
Openalex Percentile: Top 63%
Spine and Intervertebral Disc Pathology
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Outcomes comparison between novel hydroxyapatite enhanced polyetheretherketone and titanium implants after anterior lumbar interbody fusion — Yusuf Rafiqzad, Ehsan Jazini, et al. · Journal of Spine Surgery (2026) | TGRS Research Map | TGRS