Quantitative assessment of renal function and perfusion changes in membranous nephropathy using multiparametric magnetic resonance imaging

Renal biopsy has certain limitations for diagnosing membranous nephropathy, and there is an urgent need to develop a noninvasive method. Membranous nephropathy patients had higher cortex, medullary T1 mapping values and lower cortex, medullary renal blood flow values than healthy controls. Quantitative MRI parameters show potential as a noninvasive biomarker for assessing membranous nephropathy.