Phenome-Wide Mendelian Randomization Identifying Circulating Proteins for Cardiovascular Traits in Populations of African Ancestry
Multiple lines of evidence were used to interrogate proteomic determinants of cardiometabolic diseases and traits in African-ancestry populations. We highlighted actionable circulating protein targets that could represent potential drug targets for cardiovascular diseases specific to populations with African ancestry.
Authors
- Claude Bhérer (ORCID: https://orcid.org/0000-0002-2744-7246)
- Justin Pelletier (ORCID: https://orcid.org/0000-0001-7324-5226)
- Sirui Zhou (ORCID: https://orcid.org/0000-0003-4963-0815)
- Katerina Trajanoska (ORCID: https://orcid.org/0000-0002-3792-4296)
- Susannah Selber‐Hnatiw (ORCID: https://orcid.org/0000-0003-0740-107X)
- Peyton McClelland (ORCID: https://orcid.org/0009-0009-7671-8506)
- Mooser
- Daniel Taliun
- Chen-Yang Su
- Satoshi Yoshiji
Institutions
- Erasmus MC (NL)
- McGill Genome Centre (CA)
Publication Details
- Journal
- Circulation Genomic and Precision Medicine
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1161/circgen.125.005159
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00