CASP8 and CASP3 mRNA Expression in Autoimmune Lymphoproliferative Syndrome (ALPS) and Chronic Immune Thrombocytopenia (ITP)
ALPS and chronic ITP show distinct CASP8 transcriptional patterns and a shared upregulation of CASP3 at the whole-blood mRNA level. These findings are descriptive and do not directly assess caspase activation or apoptotic pathway activity; further protein- and cell subset-based studies are needed to clarify functional implications.
Authors
- Paola Montanari
- Massimiliano Bergallo (ORCID: https://orcid.org/0000-0002-9291-1332)
- Stefano Gambarino
- Ilaria Galliano (ORCID: https://orcid.org/0000-0002-1273-3178)
- Anna Pau (ORCID: https://orcid.org/0009-0002-5430-6008)
- Federico Rondot (ORCID: https://orcid.org/0000-0002-3162-9771)
- Anna Clemente
- Cristina Calvi
Institutions
- Department of Medical Sciences (BY)
- Department of Public Health (US)
- University of Turin (IT)
Publication Details
- Journal
- Genes
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3390/genes17020206
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Torino