Development and Validation of a UHPLC-MS/MS Method to Identify Interference from Qiliqiangxin Capsule and Deslanoside in Digoxin Therapeutic Drug Monitoring: A Comparison with Immunoassay

The developed UHPLC-MS/MS method was highly sensitive and time-efficient, making it a reliable tool for digoxin TDM and identifying interference from Qiliqiangxin capsule and deslanoside.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2026-02-09
DOI
https://doi.org/10.1097/ftd.0000000000001445
Primary Topic
Phytochemistry and Bioactive Compounds
Type
article
Field-Weighted Citation Impact
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article

Development and Validation of a UHPLC-MS/MS Method to Identify Interference from Qiliqiangxin Capsule and Deslanoside in Digoxin Therapeutic Drug Monitoring: A Comparison with Immunoassay

Peile Wang, Jing Yang, Zhan Wang, Guang Chen
Therapeutic Drug Monitoring
Phytochemistry and Bioactive Compounds
article

Development and Validation of a UHPLC-MS/MS Method to Identify Interference from Qiliqiangxin Capsule and Deslanoside in Digoxin Therapeutic Drug Monitoring: A Comparison with Immunoassay

Peile Wang, Jing Yang, Zhan Wang, Guang Chen
article en

Abstract

The developed UHPLC-MS/MS method was highly sensitive and time-efficient, making it a reliable tool for digoxin TDM and identifying interference from Qiliqiangxin capsule and deslanoside.

Therapeutic Drug Monitoring
Zhengzhou University (CN), First Affiliated Hospital of Zhengzhou University (CN)
Good health and well-being
Openalex Percentile: Top 64%
Phytochemistry and Bioactive Compounds
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