Distinct epigenetic aging in sporadic and hereditary neuroendocrine neoplasms

Epigenetic age and age acceleration analysis demonstrate distinct patterns in sporadic and hereditary NEN, suggesting lower impact of epigenetic alteration or DNA aging in the pathogenesis of hereditary NEN.

Authors

Reut Halperin (ORCID: https://orcid.org/0000-0002-8137-667X)
Amit Tirosh (ORCID: https://orcid.org/0000-0003-3794-9634)
Shiri Weinstein

Institutions

Tel Aviv University (IL)
Sheba Medical Center (IL)

Publication Details

Journal: Clinical Epigenetics
Published: 2026-02-09
DOI: https://doi.org/10.1186/s13148-026-02069-1
Primary Topic: Neuroendocrine Tumor Research Advances
Type: article
Field-Weighted Citation Impact: 0.00

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article

Distinct epigenetic aging in sporadic and hereditary neuroendocrine neoplasms

Reut Halperin, Amit Tirosh, Shiri Weinstein

Feb 9, 2026

Clinical Epigenetics

Neuroendocrine Tumor Research Advances

article

Distinct epigenetic aging in sporadic and hereditary neuroendocrine neoplasms

Reut Halperin, Amit Tirosh, Shiri Weinstein

February 9, 2026article en

Abstract

Clinical EpigeneticsVol. 18(1)

Tel Aviv University (IL), Sheba Medical Center (IL)

Openalex Percentile: Top 61%

Neuroendocrine Tumor Research Advances

DOI Open Access PDF OpenAlex

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Distinct epigenetic aging in sporadic and hereditary neuroendocrine neoplasms — Reut Halperin, Amit Tirosh, et al. · Clinical Epigenetics (2026) | TGRS Research Map | TGRS