Optimal surgical timing after high-altitude de-adaptation: day-30 post-descent marks physiologic recalibration and improved small bowel repair in rats

The duration of high-altitude de-adaptation is closely associated with intestinal repair quality. Approximately 30 days of normoxic re-acclimation correspond to coordinated resolution of hypoxia-related physiological perturbations and optimized tissue repair, identifying a critical post-relocation window relevant to surgical timing after descent from high altitude.