The predictive value of baseline systemic inflammation response index and systemic immune-inflammation index for the risk of infection within 6 months following initial immunosuppressive treatment in patients with ANCA-associated vasculitis
Pre-treatment SII and SIRI are independent predictors of early infection in AAV patients. The developed nomogram, which integrates these indices with age, albumin and cumulative dose of prednisone within the first month, serves as an exploratory assessment tool for individualized risk.
Authors
- Yan Xu (ORCID: https://orcid.org/0000-0003-0379-8866)
- Yujia Wang (ORCID: https://orcid.org/0000-0002-3415-8944)
- Kunmei Lai
- Caiming Chen
- Jianxin Wan
- Kaiqi Huang
- Zigui Zheng
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fimmu.2026.1718901
- Citations
- 1
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 36.44
Funders
- National Natural Science Foundation of China
- Fujian Provincial Health Commission