Early versus late initiation of long‐acting insulin in paediatric and adult diabetic ketoacidosis: A systematic review and meta‐analysis of randomised control trials

Early initiation of long-acting insulin during IV insulin infusion in DKA likely shortens time to resolution based on moderate certainty evidence and may reduce total insulin and fluid requirements. Evidence for rebound hyperglycaemia and recurrent DKA outcomes remains limited and imprecise.