Children With Biliary Atresia Have Substantial Morbidity in Early Childhood and a High Risk of Liver Transplantation

The high mortality and the substantial need for liver transplantation within the first year of life underline the severity of biliary atresia. This highlights the urgent need for further research into pregnancy exposures that may contribute to this rare but severe congenital anomaly to develop primary prevention strategies.

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Publication Details

Journal
Birth Defects Research
Published
2026-02-01
DOI
https://doi.org/10.1002/bdr2.70024
Primary Topic
Pediatric Hepatobiliary Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Children With Biliary Atresia Have Substantial Morbidity in Early Childhood and a High Risk of Liver Transplantation

Maria A. Loane, Joanne Emma Given, Joan K. Morris, David Tucker et al.
Birth Defects Research
Pediatric Hepatobiliary Diseases and Treatments
article

Children With Biliary Atresia Have Substantial Morbidity in Early Childhood and a High Risk of Liver Transplantation

Maria A. Loane, Joanne Emma Given, Joan K. Morris, David Tucker, Clara Cavero‐Carbonell, Ester Garne, Sue E. Jordan, Elisa Ballardini, A Pierini, Mika Gissler, Anke Rissmann, Joachim Tan, Mads Damkjær
article en

Abstract

The high mortality and the substantial need for liver transplantation within the first year of life underline the severity of biliary atresia. This highlights the urgent need for further research into pregnancy exposures that may contribute to this rare but severe congenital anomaly to develop primary prevention strategies.

Birth Defects ResearchVol. 118(2)
University of Ulster (GB), St George's, University of London (GB), University of Southern Denmark (DK), University of Ferrara (IT), Great Ormond Street Hospital (GB), Swansea University (GB), Finnish Institute for Health and Welfare (FI), Public Health Wales (GB), Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (ES), Istituto di Fisiologia Clinica (IT), Lillebaelt Hospital (DK), National Research Council (IT), University College London (GB), Otto-von-Guericke-Universität Magdeburg (DE)
European Commission
Good health and well-being
Openalex Percentile: Top 63%
Pediatric Hepatobiliary Diseases and Treatments
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