Cost-effectiveness of ramucirumab plus paclitaxel as maintenance therapy for patients with advanced HER2-negative gastric or gastroesophageal junction cancer

At current pricing and under the existing PAP framework, ramucirumab plus paclitaxel is not a cost-effective switch maintenance strategy in advanced HER2-negative gastric or gastroesophageal junction cancer in China. Significant price reductions through national negotiations may enable this regimen to become economically viable within the Chinese healthcare system.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-09
DOI
https://doi.org/10.3389/fonc.2026.1713870
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Cost-effectiveness of ramucirumab plus paclitaxel as maintenance therapy for patients with advanced HER2-negative gastric or gastroesophageal junction cancer

Dong Li, Xue Zhao, Liman Huo, Huixian Jia et al.
Frontiers in Oncology
Gastric Cancer Management and Outcomes
article

Cost-effectiveness of ramucirumab plus paclitaxel as maintenance therapy for patients with advanced HER2-negative gastric or gastroesophageal junction cancer

Dong Li, Xue Zhao, Liman Huo, Huixian Jia, Rong Cui, Afang Cao
article en

Abstract

At current pricing and under the existing PAP framework, ramucirumab plus paclitaxel is not a cost-effective switch maintenance strategy in advanced HER2-negative gastric or gastroesophageal junction cancer in China. Significant price reductions through national negotiations may enable this regimen to become economically viable within the Chinese healthcare system.

Frontiers in OncologyVol. 16
Hebei Medical University (CN), Second Hospital of Hebei Medical University (CN), Fourth Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 64%
Gastric Cancer Management and Outcomes
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