Efficacy of platelet-rich therapies versus placebo in the treatment of erectile dysfunction: an updated systematic review and meta-analysis of randomized controlled trials

This meta-analysis of RCTs provides low-to-moderate certainty evidence that PRTs do not confer superior efficacy over placebo in improving sexual function in men with ED. However, the small number of patients restricts the generalizability of our conclusions. Additional high-quality studies are required to clarify the clinical role of PRTs in the management of ED.

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Publication Details

Journal
The Journal of Sexual Medicine
Published
2026-01-22
DOI
https://doi.org/10.1093/jsxmed/qdag019
Primary Topic
Sexual function and dysfunction studies
Type
article
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article

Efficacy of platelet-rich therapies versus placebo in the treatment of erectile dysfunction: an updated systematic review and meta-analysis of randomized controlled trials

Fernando Cruvinel de Freitas, Thairo A. Pereira, Murilo Ribeiro Sanches, Augusto Barbosa Reis et al.
The Journal of Sexual Medicine
Sexual function and dysfunction studies
article

Efficacy of platelet-rich therapies versus placebo in the treatment of erectile dysfunction: an updated systematic review and meta-analysis of randomized controlled trials

Fernando Cruvinel de Freitas, Thairo A. Pereira, Murilo Ribeiro Sanches, Augusto Barbosa Reis, Lucas G. C. R. de Amorim, H L Bernie
article en

Abstract

This meta-analysis of RCTs provides low-to-moderate certainty evidence that PRTs do not confer superior efficacy over placebo in improving sexual function in men with ED. However, the small number of patients restricts the generalizability of our conclusions. Additional high-quality studies are required to clarify the clinical role of PRTs in the management of ED.

The Journal of Sexual MedicineVol. 23(3)
Universidade Federal de Minas Gerais (BR), Indiana University Health (US), Indiana University – Purdue University Indianapolis (US), Universidade Federal de Goiás (BR)
Gender equality
Openalex Percentile: Top 64%
Sexual function and dysfunction studies
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