New Synthesis of 5-Arylfuran-2,3-diones

Abstract Literature data on the main preparative methods of synthesis of 5-arylfuran-2,3-diones have been considered. A new convenient protocol has been proposed for the synthesis of these compounds by heating 4-aryl-2,4-dioxobutanoic acids with acetyl bromide in anhydrous chloroform under reflux conditions. The structure of 5-(4-methoxyphenyl)furan-2,3-dione has been confirmed by X-ray analysis.

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Publication Details

Journal
Russian Journal of Organic Chemistry
Published
2025-12-01
DOI
https://doi.org/10.1134/s1070428025603905
Primary Topic
Chemical synthesis and pharmacological studies
Type
article
Field-Weighted Citation Impact
0.00

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article

New Synthesis of 5-Arylfuran-2,3-diones

Y. V. Shklyaev, A. N. Maslivets, A. O. Derevnina
Russian Journal of Organic Chemistry
Chemical synthesis and pharmacological studies
article

New Synthesis of 5-Arylfuran-2,3-diones

Y. V. Shklyaev, A. N. Maslivets, A. O. Derevnina
article en

Abstract

Abstract Literature data on the main preparative methods of synthesis of 5-arylfuran-2,3-diones have been considered. A new convenient protocol has been proposed for the synthesis of these compounds by heating 4-aryl-2,4-dioxobutanoic acids with acetyl bromide in anhydrous chloroform under reflux conditions. The structure of 5-(4-methoxyphenyl)furan-2,3-dione has been confirmed by X-ray analysis.

Russian Journal of Organic ChemistryVol. 61(12)
Perm State University (RU), Institute of Technical Chemistry (RU), Solikamsk State Pedagogical Institute (RU)
Ministry of Science and Higher Education of the Russian Federation
Openalex Percentile: Top 31%
Chemical synthesis and pharmacological studies
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