Effect of polymorphic variants of genes of neurotrophic factors on the disease severity and the anxiety level in patients with affective disorders and comorbid alcohol dependence

The polymorphic variants rs3924999 of the <i>NRG1</i> gene and rs6330 of the <i>NGF</i> gene are associated with less severe depressive symptoms and a lower level of anxiety in patients with AfD and AfD combined with AlD.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2026-02-09
DOI
https://doi.org/10.17116/jnevro2026126011126
Primary Topic
Nerve injury and regeneration
Type
article
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article

Effect of polymorphic variants of genes of neurotrophic factors on the disease severity and the anxiety level in patients with affective disorders and comorbid alcohol dependence

E V Mikhalitskaya, S N Vasilyeva, N M Vyalova, G G Simutkin et al.
S S Korsakov Journal of Neurology and Psychiatry
Nerve injury and regeneration
article

Effect of polymorphic variants of genes of neurotrophic factors on the disease severity and the anxiety level in patients with affective disorders and comorbid alcohol dependence

E V Mikhalitskaya, S N Vasilyeva, N M Vyalova, G G Simutkin, O V Roshchina, S A Ivanova
article en

Abstract

The polymorphic variants rs3924999 of the <i>NRG1</i> gene and rs6330 of the <i>NGF</i> gene are associated with less severe depressive symptoms and a lower level of anxiety in patients with AfD and AfD combined with AlD.

S S Korsakov Journal of Neurology and PsychiatryVol. 126(1)
Russian Academy of Sciences (RU), Mental Health Research Institute (AU), Siberian State Medical University (RU), Tomsk National Research Medical Center (RU)
Good health and well-being
Openalex Percentile: Top 64%
Nerve injury and regeneration
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