Evaluating treatment effectiveness: Complementing RCTs with real-world data

As the need for RWD increases, especially for post-COVID-19 pandemic decision-making, ensuring high data quality and appropriate study design is critical. Proper evaluation of RWD sources enhances the credibility of findings and supports their use in meta-analyses, clinical guidelines, and healthcare policy.

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Publication Details

Journal
American Journal of Health-System Pharmacy
Published
2026-02-05
DOI
https://doi.org/10.1093/ajhp/zxag035
Primary Topic
Meta-analysis and systematic reviews
Type
article
Field-Weighted Citation Impact
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article

Evaluating treatment effectiveness: Complementing RCTs with real-world data

Stephanie H. Read, Christina G. Rivera, André C. Kalil, Essy Mozaffari
American Journal of Health-System Pharmacy
Meta-analysis and systematic reviews
article

Evaluating treatment effectiveness: Complementing RCTs with real-world data

Stephanie H. Read, Christina G. Rivera, André C. Kalil, Essy Mozaffari
article en

Abstract

As the need for RWD increases, especially for post-COVID-19 pandemic decision-making, ensuring high data quality and appropriate study design is critical. Proper evaluation of RWD sources enhances the credibility of findings and supports their use in meta-analyses, clinical guidelines, and healthcare policy.

American Journal of Health-System Pharmacy
Mayo Clinic in Arizona (US), Gilead Sciences (Australia) (AU), University of Nebraska Medical Center (US)
Good health and well-being
Openalex Percentile: Top 65%
Meta-analysis and systematic reviews
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Evaluating treatment effectiveness: Complementing RCTs with real-world data — Stephanie H. Read, Christina G. Rivera, et al. · American Journal of Health-System Pharmacy (2026) | TGRS Research Map | TGRS