Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays

We refitted the ABIDE model, predicting MCI to dementia progression, with automated CSF measurements. The model was well calibrated in amyloid-positive patients and may support clinical discussions regarding ATTs.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2026-02-01
DOI
https://doi.org/10.1002/alz.71192
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays

Géraldine Poisnel, B. Vellas, L. Spiru, Wolfgang Maier et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays

Géraldine Poisnel, B. Vellas, L. Spiru, Wolfgang Maier, Dina L. Silva, E Rüther, Erik Stormrud, Inês Baldeiras, Oskar H. Hansson, Åsa Wallin, P. J. Visser, Stephanie J B Vos, Sanna-Kaisa Herukka, Simon Lovestone, Giovanni B Frisoni, Ingrid S van Maurik, Gael Chetelat, Magda Tsolaki, Oliver Peters, Iwona Kłoszewska, Samantha Galluzzi, Charlotte E Teunissen, Johannes Kornhuber, Jens Wiltfang, Isabel Santana, Argonde C van Harten, Frederik Barkhof, Pieter J van der Veere, Alexandre de Mendonca, Patrizia Mecocci, Sebastian Palmqvist, Sterling C Johnson
article en

Abstract

We refitted the ABIDE model, predicting MCI to dementia progression, with automated CSF measurements. The model was well calibrated in amyloid-positive patients and may support clinical discussions regarding ATTs.

Alzheimer s & DementiaVol. 22(2)
University of Geneva (CH), Alzheimer's Association (US), University of Wisconsin–Madison (US), University of Lisbon (PT), Inserm (FR), Carol Davila University of Medicine and Pharmacy (RO), University of Eastern Finland (FI), Université Fédérale de Toulouse Midi-Pyrénées (FR), Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Malmö University (SE), King's College London (GB), Lund University (SE), Aristotle University of Thessaloniki (GR), Heidelberg University (DE), Örebro University (SE), University of Perugia (IT), German Center for Neurodegenerative Diseases (DE), Hospitais da Universidade de Coimbra (PT), University Hospital Heidelberg (DE), Karolinska Institutet (SE), Maastricht University (NL), Humboldt-Universität zu Berlin (DE), Sorbonne Université (FR), University of Oxford (GB), Azienda Ospedaliera di Perugia (IT), Hospital Universitari de Santa Maria (ES), International Longevity Centre (GB), Northwest Hospital (US), Central Institute of Mental Health (DE), Alzheimer’s Disease Neuroimaging Initiative (US), Normandie Université (FR), University Hospital of Geneva (CH), Amsterdam Neuroscience (NL), Centro San Giovanni di Dio Fatebenefratelli (IT), Ospedale Santa Maria (IT), Pitié-Salpêtrière Hospital (FR), Medical University of Lodz (PL), Skåne University Hospital (SE), The London College (GB), GGD Amsterdam (NL), Amsterdam University Medical Centers (NL), Fundació Clínic per a la Recerca Biomèdica (ES), Alzheimer Precision Medicine (FR), University College London (GB), University of Aveiro (PT), University of Algarve (PT), University of Göttingen (DE), University of Coimbra (PT), Vrije Universiteit Amsterdam (NL), Université de Caen Normandie (FR)
U.S. Department of Defense, Alzheimer's Association, Bristol-Myers Squibb, Eli Lilly and Company, Biogen, F. Hoffmann-La Roche, BioClinica, GHR Foundation, European Commission, Lunds Universitet, Vetenskapsrådet, National Institutes of Health, Genentech, HORIZON EUROPE Framework Programme, National Institute on Aging
Openalex Percentile: Top 64%
Dementia and Cognitive Impairment Research
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