The clinical significance of miR-484 in depression of older people with Alzheimer’s disease and its potential role on depressive behavior

Downregulated miR-484 expression, correlating with cognitive function and depression degree, showed a diagnostic value on AD and AD-D. MiR-484 attenuated the CRS-induced depression-like behavior by regulating PDGFA.

Authors

Institutions

Publication Details

Journal
Psychiatric Genetics
Published
2026-01-21
DOI
https://doi.org/10.1097/ypg.0000000000000411
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The clinical significance of miR-484 in depression of older people with Alzheimer’s disease and its potential role on depressive behavior

Shuai Teng, Jingxia Ma, Pingjing Jiang, Xichun Wang et al.
Psychiatric Genetics
Neurological Disease Mechanisms and Treatments
article

The clinical significance of miR-484 in depression of older people with Alzheimer’s disease and its potential role on depressive behavior

Shuai Teng, Jingxia Ma, Pingjing Jiang, Xichun Wang, Ying Li
article en

Abstract

Downregulated miR-484 expression, correlating with cognitive function and depression degree, showed a diagnostic value on AD and AD-D. MiR-484 attenuated the CRS-induced depression-like behavior by regulating PDGFA.

Psychiatric Genetics
Jinan University (CN), Chongqing City Mental Health Center (CN), Shenzhen KangNing Hospital (CN), Weifang University (CN)
Good health and well-being
Openalex Percentile: Top 69%
Neurological Disease Mechanisms and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.