Stage at Diagnosis and International Survival Variation in Childhood Tumors in the BENCHISTA Study
In this BENCHISTA cohort study of 6 solid tumors, international variation in population-level OS was associated with differences in tumor stage distribution for some cancer types and regions. Additional factors are suggested for further investigation. The results have important implications for national health systems for monitoring early diagnosis efforts and supporting collaboration between CRs and clinicians to sustain standardized use of Toronto guidelines to improve understanding of survival variation in childhood cancer.
Authors
- Cristiane Bastos Daniel
- Cros Carulla Mj
- Bernward Zeller (ORCID: https://orcid.org/0000-0001-9008-4495)
- Lucy Irvine (ORCID: https://orcid.org/0000-0001-5369-6281)
- A. De Aquino
- Adela Cañete Nieto
- Miriam J Azzopardi
- Noura Jeghalef-El Karoui
- Stephanie Smits (ORCID: https://orcid.org/0000-0001-7897-150X)
- Keiu Paapsi (ORCID: https://orcid.org/0000-0003-1458-3254)
- L. Mangone
- Zsuzsanna Jakab
- William Mantovani (ORCID: https://orcid.org/0009-0005-4256-9953)
- Rebeca Valentim Leite
- Luciana Ferreira dos Santos (ORCID: https://orcid.org/0009-0009-5799-0416)
- Patrizia Piga
- Mihaela Bucurenci
- B. Lacour
- Deidre Fitzpatrick
- Antonina Torrisi
- Alekhin Di
- Paulo César Fernandes de Souza (ORCID: https://orcid.org/0000-0002-0032-1125)
- Damien Bennett (ORCID: https://orcid.org/0000-0003-2053-7078)
- D. B Veneziano
- David Parra-Blazquez
- Dahlen Al
- Daniela Piras (ORCID: https://orcid.org/0009-0002-2606-7716)
- Rosalia Ragusa (ORCID: https://orcid.org/0000-0002-0964-3438)
- Angela Lopez-Cortes (ORCID: https://orcid.org/0000-0001-7334-3555)
- Ramos Wf
- J. Starý
- Sandra J. Strauss (ORCID: https://orcid.org/0000-0001-8328-0260)
- Marcella Sessa (ORCID: https://orcid.org/0000-0002-1402-7525)
- David Morrison (ORCID: https://orcid.org/0000-0002-0617-3047)
- Giles Greene (ORCID: https://orcid.org/0000-0001-9326-8740)
- Danny R. Youlden (ORCID: https://orcid.org/0000-0002-2721-9083)
- Jason D. Pole (ORCID: https://orcid.org/0000-0002-0413-5434)
- M. Ressing
- C. Laporte
- L. Botta
- Caldas Gc
- Carlos Anselmo Lima
- Angela Polanco (ORCID: https://orcid.org/0000-0002-4619-0773)
- Emmanuel Désandes (ORCID: https://orcid.org/0000-0002-7842-2858)
- Päivi M. Lähteenmäki (ORCID: https://orcid.org/0000-0002-5500-9606)
- Gianbattista Spagnoli
- Simon Bailey
- Charles Stiller (ORCID: https://orcid.org/0000-0002-3006-7869)
- Claire Poulalhon (ORCID: https://orcid.org/0000-0001-7017-8080)
- Lisa Lyngsie Hjalgrim (ORCID: https://orcid.org/0000-0001-5186-3365)
- Adele Caldarella (ORCID: https://orcid.org/0000-0003-3439-2295)
- Donato Bruno
- B. Working Group
- RAIMUNDA NONATA DE PAULO
- Giuseppe Sampietro (ORCID: https://orcid.org/0000-0001-8173-7810)
- Lucrécia Aline Cabral Formigosa (ORCID: https://orcid.org/0000-0003-4245-672X)
- Deidre M. Murray
- Teresa Intrieri
- Eugenia Spata
- Luca Boni
- Otto Visser
- Monika Hackl
- María Dolores Chirlaque
- Marceli de Oliveira Santos
- Kayo Nakata
- Nathalie Gaspar
- Pasquala Pinna
- Fabio Didonè
- Zsusanna Jakab
- Sonia Manasse
- Fabio Falcini
- Luigino Dal Maso
- Tiziana Scuderi
- Nuria Aragonés
- M Maule
- T. B. Johannesen
- Rocco Galasso
- Joanne F Aitken
- Gemma Gatta
- Sarah Stevens
- Fabrizio Stracci
- Daniela Coza
- Dyfed Wyn Huws
- Marcela Guevara
- Ana M. Ferreira
- Ruth Ladenstein
- Riccardo Capocaccia
- Jerzy Kowalczyk
- Anna Gavin
- Elena Pardo
- Francesca Bella
- Stefano Ferretti
- Jeanette Falck Winther
- Sumit Gupta
- Paolo Coccia
- Eleni T. Petridou
- Leisa O'Neil
- Maria Jose Sanchez
- Meric Klein
- Henrike Karim-Kos
- Shelagh M. Redmond
- Carlotta Sacerdote
- Evdoxia Bouka
- Rosalba Amodio
- Anna Raciborska
- Elizabeth Van Eycken
- Cristiana Santos de Menezes Miranda
- Francesco Cuccaro
- Claudina Agnese Casale
- Karen Smith
- Gil Patrus Pena
- Montse Puigdemonte
- Claudia Truenbach
- Jacqueline Clavel
- Claudia E. Kuehni
- Federico Gervasi
- Nancy Van Damme
- Claudia Spix
- Manuel Zorzi
- Fernando Alemda-Vich
- Miklos Garami
- Magda Rognomi
- Antonio G Russo
- Juliana Nativio
- Beatriz De Camargo
- Tomohiro Matsuda
- Dobrin Konstantinov
Institutions
- Semmelweis University (HU)
- University of Copenhagen (DK)
- Oslo University Hospital (NO)
- Inserm (FR)
- Université Paris Cité (FR)
- Royal Victoria Infirmary (GB)
- Istituto Giannina Gaslini (IT)
- Institut Gustave Roussy (FR)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Hospital Universitari i Politècnic La Fe (ES)
- Sorbonne Paris Cité (FR)
- Institut de Cancérologie de Lorraine (FR)
- Media Working Group (US)
- National Institute of Oncology (HU)
- CRUK Lung Cancer Centre of Excellence (GB)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- National Cancer Registration Service (GB)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Centre de Recherche Épidémiologie et Statistique (FR)
- University College London (GB)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.56747
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 41.85