Influence of Chronic Lymphocytic Thyroiditis and BRAF V600E Mutation on Clinicopathological Features in Papillary Thyroid Carcinoma With Different Tumor Size
The presence of CLT appears to exert a protective effect in PTC. However, the prognostic significance of <i>BRAF V600E</i> mutation varies with tumor size. While CLT-related inflammatory microenvironment may counteract tumor progression in small cancers, it seems insufficient to mitigate the aggressive behavior driven by <i>BRAF V600E</i> mutation in larger tumors.
Authors
- J. Ye
- Yuxin Yang (ORCID: https://orcid.org/0000-0002-1742-2328)
- Wan-Xiao Wu
- Y F Jiang
- Jia-Wei Feng
Institutions
- Soochow University (CN)
- The First People's Hospital of Changzhou (CN)
- First Affiliated Hospital of Soochow University (CN)
- Changzhou Third People's Hospital (CN)
Publication Details
- Journal
- Annali Italiani di Chirurgia
- Published
- 2026-02-09
- DOI
- https://doi.org/10.62713/aic.4363
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00