Global incidence of acute kidney injury and renal replacement therapy among obstetric intensive care unit admissions: a systematic review and meta-analysis

Among obstetric patients admitted to intensive care units, maternal AKI represents a substantial clinical burden, with a significant proportion of affected women requiring RRT-a marker of disease severity strongly associated with increased mortality. Despite generally favorable renal recovery among survivors, profound regional disparities persist. These estimates apply exclusively to obstetric ICU admissions and should not be extrapolated to the general pregnant population. Early identification, standardized diagnostic criteria, and equitable access to renal replacement therapies remain critical priorities to improve maternal outcomes in intensive care settings.