Cuproptosis-related gene signatures define immune subtypes and predict prognosis in gastric cancer
The identified cuproptosis-related gene signature is associated with the immunological heterogeneity of gastric cancer. Together, these results point to previously unrecognized links between cuproptosis and antitumor immunity, may provide insights for refining immunotherapeutic strategies in gastric cancer. Continued experimental investigation will be necessary to unravel how cuproptosis contributes to gastric cancer development and to validate its association with immune regulation.
Authors
- Yuxin Man
- Dao Xin (ORCID: https://orcid.org/0000-0002-6172-7727)
- Bingtong Yue
- Min Liu
- Zhe Wang
- Jiayi Zhang
- Feng Wang
Institutions
- Sun Yat-sen University (CN)
- Henan Tianguan Group (China) (CN)
- Sichuan Cancer Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- Ministry of Education (ET)
- First Affiliated Hospital of Zhengzhou University (CN)
- Anyang Tumor Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fmolb.2026.1746613
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation
- Henan Provincial Science and Technology Research Project