Effectiveness of Indapamide Prolonged‐Release and Perindopril Versus Perindopril Monotherapy for Treated Uncontrolled Hypertension: A Target Trial Emulation
Target trial emulation allowed assessment of antihypertensive treatment effectiveness, and indapamide plus perindopril yielded clinically meaningful decreases in SBP over perindopril monotherapy. Secondary and sensitivity analyses support that these findings were robust.
Authors
- Manel Pladevall (ORCID: https://orcid.org/0000-0002-9359-6055)
- Xabier García‐Albéniz (ORCID: https://orcid.org/0000-0002-9814-2343)
- Dominique Procureur
- Jaume Miralles Aguado
- Emmanuelle Jacquot
- Marie Mangin
- Céline Darricarrère (ORCID: https://orcid.org/0000-0002-5306-6906)
- Virginie Simon
- Morgane Ballon
Institutions
- Hôpital américain de paris (FR)
- Henry Ford Health System (US)
- Servier (France) (FR)
- Life Cycle Engineering (United States) (US)
Publication Details
- Journal
- Pharmacoepidemiology and Drug Safety
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/pds.70295
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Servier