Unsuppressed Viremia and Lower CD4 Count Associated With Faster Telomere Attrition in African Children With Perinatal Human Immunodeficiency Virus on Long-term Antiretroviral Therapy

HIV VL>1000 copies/mL among CWH on cART in Africa is associated with a degradation of immune age within one year, which may increase risk of co-morbidities later in life.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2026-02-05
DOI
https://doi.org/10.1093/infdis/jiag060
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
0.00
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article

Unsuppressed Viremia and Lower CD4 Count Associated With Faster Telomere Attrition in African Children With Perinatal Human Immunodeficiency Virus on Long-term Antiretroviral Therapy

Nyasha V Dzavakwa, Hildah Banda Mabuda, Lackson Kasonka, L Chetham et al.
The Journal of Infectious Diseases
Telomeres, Telomerase, and Senescence
article

Unsuppressed Viremia and Lower CD4 Count Associated With Faster Telomere Attrition in African Children With Perinatal Human Immunodeficiency Virus on Long-term Antiretroviral Therapy

Nyasha V Dzavakwa, Hildah Banda Mabuda, Lackson Kasonka, L Chetham, Emily Carr, Julian P G Shellard, Gianni Tam-McMillan, Emma W Mao, Hilda Angela Mujuru, Rashida A Ferrand, Victoria Simms, Anthony Y Y Hsieh, Celia L Gregson
article en

Abstract

HIV VL>1000 copies/mL among CWH on cART in Africa is associated with a degradation of immune age within one year, which may increase risk of co-morbidities later in life.

The Journal of Infectious Diseases
University of Zimbabwe (ZW), St George's, University of London (GB), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Nuffield Orthopaedic Centre (GB), University Teaching Hospital (ZM), University of Bristol (GB), University of Oxford (GB), London School of Hygiene & Tropical Medicine (GB), Biomedical Research and Training Institute (ZW), City St George's, University of London (GB)
Zero hunger
Openalex Percentile: Top 61%
Telomeres, Telomerase, and Senescence
DOIOpen Access PDFOpenAlex
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Unsuppressed Viremia and Lower CD4 Count Associated With Faster Telomere Attrition in African Children With Perinatal Human Immunodeficiency Virus on Long-term Antiretroviral Therapy — Nyasha V Dzavakwa, Hildah Banda Mabuda, et al. · The Journal of Infectious Diseases (2026) | TGRS Research Map | TGRS