Evaluation of the relationship between salivary levels of Streptococcus mutans, statherin, and cathelicidin LL-37 and early childhood caries

There was no statistically significant difference in salivary statherin levels between the two groups, but salivary cathelicidin LL-37 levels were significantly higher in the ECC group (p = 0.024). The ECC group had significantly elevated S. mutans levels compared to the non-ECC group (p < 0.05). The frequency of sugar-containing foods and/or beverages consumed more than three times a day between meals was statistically significantly higher in the ECC group compared to the non-ECC group (p = 0.021). The statistical analysis also revealed a positive correlation between the dmfs score and age (p = 0.022).

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Publication Details

Journal
BMC Oral Health
Published
2026-02-09
DOI
https://doi.org/10.1186/s12903-026-07819-4
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
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article

Evaluation of the relationship between salivary levels of Streptococcus mutans, statherin, and cathelicidin LL-37 and early childhood caries

Nazan Ersın, ceren pamuk, Gülnur Emingil, Cansu Vural et al.
BMC Oral Health
Oral microbiology and periodontitis research
article

Evaluation of the relationship between salivary levels of Streptococcus mutans, statherin, and cathelicidin LL-37 and early childhood caries

Nazan Ersın, ceren pamuk, Gülnur Emingil, Cansu Vural, Güven Özdemir, Caner Vural, Aytül Gül, Handan Çelik, Yüksel Gezgin
article en

Abstract

There was no statistically significant difference in salivary statherin levels between the two groups, but salivary cathelicidin LL-37 levels were significantly higher in the ECC group (p = 0.024). The ECC group had significantly elevated S. mutans levels compared to the non-ECC group (p < 0.05). The frequency of sugar-containing foods and/or beverages consumed more than three times a day between meals was statistically significantly higher in the ECC group compared to the non-ECC group (p = 0.021). The statistical analysis also revealed a positive correlation between the dmfs score and age (p = 0.022).

BMC Oral Health
Izmir University (TR), Ege University (TR), Istinye University (TR), Pamukkale University (TR)
Zero hunger
Openalex Percentile: Top 62%
Oral microbiology and periodontitis research
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Evaluation of the relationship between salivary levels of Streptococcus mutans, statherin, and cathelicidin LL-37 and early childhood caries — Nazan Ersın, ceren pamuk, et al. · BMC Oral Health (2026) | TGRS Research Map | TGRS