Micronuclei in the Buccal Mucosal Cells are Genotoxicity Markers in Oral Potentially Malignant Disorders: A Systematic Review and Meta-Analysis

Micronuclei genotoxicity is emerging as a valuable biomarker for the early detection of OPMD's. Due to its non-invasive and cost-efficient characteristics, examining micronuclei in exfoliated buccal cells could be incorporated into regular screenings for groups at high risk of OPMD and oral cancer. However, the considerable variability among studies necessitates careful interpretation and highlights the importance of establishing standardized protocols in future research.