Successful Vaginal Delivery in a Pregnant Woman With Bernard–Soulier Syndrome: A Case Report

Bernard-Soulier syndrome (BSS) is a rare inherited platelet disorder that poses major risks during pregnancy because of potential bleeding complications. Managing such cases in low-resource settings is especially challenging. We report the case of a 23-year-old Afghan woman with BSS who achieved a successful full-term vaginal delivery at a tertiary center. Early referral, coordinated management by hematology and obstetric teams, prophylactic platelet transfusions, and prompt treatment of postpartum hemorrhage led to a favorable maternal and neonatal outcome. This experience shows that, even where advanced laboratory and transfusion resources are limited, structured planning, timely communication, and preparedness can ensure a safe delivery for women with complex hematologic disorders.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/ccr3.71706
Primary Topic
Platelet Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Successful Vaginal Delivery in a Pregnant Woman With Bernard–Soulier Syndrome: A Case Report

Ezat Hajmollarezaei, Monireh Yaghoubi, Nona Sabeti
Clinical Case Reports
Platelet Disorders and Treatments
article

Successful Vaginal Delivery in a Pregnant Woman With Bernard–Soulier Syndrome: A Case Report

Ezat Hajmollarezaei, Monireh Yaghoubi, Nona Sabeti
article en

Abstract

Bernard-Soulier syndrome (BSS) is a rare inherited platelet disorder that poses major risks during pregnancy because of potential bleeding complications. Managing such cases in low-resource settings is especially challenging. We report the case of a 23-year-old Afghan woman with BSS who achieved a successful full-term vaginal delivery at a tertiary center. Early referral, coordinated management by hematology and obstetric teams, prophylactic platelet transfusions, and prompt treatment of postpartum hemorrhage led to a favorable maternal and neonatal outcome. This experience shows that, even where advanced laboratory and transfusion resources are limited, structured planning, timely communication, and preparedness can ensure a safe delivery for women with complex hematologic disorders.

Clinical Case ReportsVol. 14(2)
Mashhad University of Medical Sciences (IR)
Openalex Percentile: Top 61%
Platelet Disorders and Treatments
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