<scp>CRP</scp> , <scp>NLR</scp> , and <scp>PLR</scp> Dynamics in Non‐Metastatic Breast Cancer Patients Receiving Chemotherapy: Associations With Nutritional and Clinical Factors
Early within-treatment monitoring revealed a stable elevation of CRP and modest upward trends in NLR/PLR from C1 to C3, with BMI associated with CRP after adjustment. CRP also exhibited greater short-term stability than NLR/PLR. Although limited by small sample size and two time points, these findings are hypothesis-generating and support larger, multi-center studies with denser sampling and longer follow-up to clarify prognostic value and inform personalized supportive care.
Authors
- N D'agostini
- Raphael Manhães Pessanha (ORCID: https://orcid.org/0000-0001-6893-0755)
- Karolini Zuqui Nunes (ORCID: https://orcid.org/0000-0003-3433-4925)
- Letícia Batista de Azevedo (ORCID: https://orcid.org/0000-0002-7810-0621)
- Karoline Neumann Gomes (ORCID: https://orcid.org/0009-0003-8141-5880)
- Júlia Anhoque Cavalcanti Marcarini (ORCID: https://orcid.org/0000-0002-2127-6626)
- Wesley Rocha Grippa (ORCID: https://orcid.org/0000-0003-3572-6031)
- Luís Carlos Lopes‐Júnior
- Andressa Bolsoni‐Lopes
- Luiz Claudio Barreto Silva Neto
Institutions
- World Health Organization Regional Office for the Americas (US)
- Universidade Federal do Espírito Santo (BR)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cam4.71601
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa e Inovação do Espírito Santo