Drug‐Resistant Sinus Tachycardia as a Dose‐Dependent Side Effect of Spironolactone: A Case Report and Review of the Literature

Spironolactone is widely used for polycystic ovarian syndrome due to its anti-androgenic properties. However, rare cardiovascular side effects may occur even in normotensive patients. We report a case of severe palpitations and drug-resistant sinus tachycardia following high-dose therapy, emphasizing the need for cautious titration and cardiac monitoring.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/ccr3.71875
Citations
1
Primary Topic
Cardiovascular Syncope and Autonomic Disorders
Type
article
Field-Weighted Citation Impact
39.15
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article

Drug‐Resistant Sinus Tachycardia as a Dose‐Dependent Side Effect of Spironolactone: A Case Report and Review of the Literature

Maryam Chenaghlou, Aysa rezabakhsh, Laya Hooshmand Gharabagh, Zahra Abdi
1 citations
Clinical Case Reports
Cardiovascular Syncope and Autonomic Disorders
39.15
article

Drug‐Resistant Sinus Tachycardia as a Dose‐Dependent Side Effect of Spironolactone: A Case Report and Review of the Literature

Maryam Chenaghlou, Aysa rezabakhsh, Laya Hooshmand Gharabagh, Zahra Abdi
article en
1 citations

Abstract

Spironolactone is widely used for polycystic ovarian syndrome due to its anti-androgenic properties. However, rare cardiovascular side effects may occur even in normotensive patients. We report a case of severe palpitations and drug-resistant sinus tachycardia following high-dose therapy, emphasizing the need for cautious titration and cardiac monitoring.

Clinical Case ReportsVol. 14(2)
Tabriz University of Medical Sciences (IR), Imam Khomeini Hospital (IR), Urmia University (IR), Urmia University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 1%
Cardiovascular Syncope and Autonomic Disorders
39.15
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