Conservative Oxygen Targets in Mechanically Ventilated Patients (OXY-BREATHES): A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Conservative oxygenation is comparable to liberal oxygen targets in mechanically ventilated critically ill patients, with possible advantages in sepsis and post-cardiac arrest. Future condition-specific RCTs are warranted to define optimal ICU oxygen strategies.

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Publication Details

Journal
Critical Care Medicine
Published
2026-02-09
DOI
https://doi.org/10.1097/ccm.0000000000007031
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Conservative Oxygen Targets in Mechanically Ventilated Patients (OXY-BREATHES): A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Jafar Aljazeeri, Nhan Nguyen, Victoria Ho, Yacin Zawam et al.
Critical Care Medicine
Respiratory Support and Mechanisms
article

Conservative Oxygen Targets in Mechanically Ventilated Patients (OXY-BREATHES): A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Jafar Aljazeeri, Nhan Nguyen, Victoria Ho, Yacin Zawam, Vy Ngoc Dan Nguyen, D Downes, N B Tran, Nathalia Alves de Barros E Lyra, Ha Duc Thien Le
article en

Abstract

Conservative oxygenation is comparable to liberal oxygen targets in mechanically ventilated critically ill patients, with possible advantages in sepsis and post-cardiac arrest. Future condition-specific RCTs are warranted to define optimal ICU oxygen strategies.

Critical Care Medicine
University of Debrecen (HU), The University of Melbourne (AU), Military Hospital (PK), Faculdade Frassinetti do Recife (BR), University of Pittsburgh Medical Center (US), Southern Ohio Medical Center (US), Faculdade Pernambucana de Saúde, Drexel University (US), University of New England (AU)
Good health and well-being
Openalex Percentile: Top 65%
Respiratory Support and Mechanisms
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Conservative Oxygen Targets in Mechanically Ventilated Patients (OXY-BREATHES): A Systematic Review and Meta-Analysis of Randomized Controlled Trials — Jafar Aljazeeri, Nhan Nguyen, et al. · Critical Care Medicine (2026) | TGRS Research Map | TGRS