Activation of NF-κB signaling in tissue-resident memory T cells promotes recurrent psoriasis in mice
Together, these findings suggest that canonical and non-canonical NF-κB signaling directly activates Trm cell differentiation, inhibits cellular cuproptosis, and promotes recurrent psoriasis.
Authors
- Siyuan Xu (ORCID: https://orcid.org/0000-0003-3385-3862)
- Han Du (ORCID: https://orcid.org/0009-0000-5415-0280)
- Feifei Qiu (ORCID: https://orcid.org/0009-0000-1431-6944)
- Jie Chen (ORCID: https://orcid.org/0000-0003-3435-0351)
- Zhaolin Liu (ORCID: https://orcid.org/0000-0001-6161-766X)
- Xuejia Li
- Yongdan Li
- Yuchao Chen
- Yukang Lin
- Huazhen Liu
- Lingling Wen
Institutions
- Guangzhou University of Chinese Medicine (CN)
- The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine (CN)
- Shenzhen Pingle Orthopedic Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1762269
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00