Low-grade inflammatory parameters may be associated with recent suicide attempts – a naturalistic study among psychiatric inpatients with depressive disorders

Although elevated low-grade inflammatory parameters, particularly NLR and MLR, were observed in depressed patients with a recent suicide attempt, this study does not provide conclusive evidence for a direct association between suicide attempts and the investigated immune markers. Further research is needed to clarify this relationship between low-grade immune parameters and acute suicide attempts, to elucidate potential causal mechanisms, and to determine their relevance and clinical applicability as biomarkers of suicidal behavior.