Diversity of Cortical Progenitors Directs Neuronal Layer Formation and Regional Glial Patterning
This dataset contains bulk RNA-seq data from GFP⁺ NG2⁺ or GFAP⁺ cells isolated by FACS following StarTrack labeling by in utero electroporation (IUE) at embryonic day E12, with cortical tissue dissociated at E14. A total of 10 samples are included (5 NG2⁺ and 5 GFAP⁺ biological replicates). An Excel file (data_counts_fpkm) is provided containing gene-level raw read counts (*_count) and normalized expression values (*_fpkm) for each replicate. The file also includes differential expression analysis results for NG2 vs GFAP and GFAP vs NG2 comparisons (log2 fold change, p-values, and adjusted p-values), as well as gene annotations including gene name, chromosomal location, strand, gene length, biotype, functional description, and transcription factor family. Raw sequencing data are provided as paired-end compressed FASTQ files (.fq.gz), where _1 and _2 correspond to forward (R1) and reverse (R2) reads from the same biological sample.
Authors
- Sonsoles Barriola (ORCID: https://orcid.org/0000-0002-1185-1658)
- Laura López-Mascaraque
- Ana Cristina Ojalvo Sanz
- Carolina Pernia-Solanilla
- María Figueres-Oñate
- Lina Maria Delgado Garcia
- Rebeca Sanchez González
Institutions
- Instituto Cajal (ES)
- Centro Universitário Internacional (MX)
Publication Details
- Journal
- DIGITAL.CSIC (Spanish National Research Council (CSIC))
- Published
- 2026-02-09
- DOI
- https://doi.org/10.5281/zenodo.18537989
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00