Antithrombotic therapy in infective endocarditis: Long-term clinical outcomes of a retrospective cohort study

In this retrospective cohort, anticoagulated patients did not show a higher rate of adverse events during hospitalization and had a lower long-term event rate. These findings represent correlations observed in a non-randomized, single-center setting and may partly reflect differences in underlying risk profiles and treatment selection (confounding by indication and residual confounding). Prospective studies are needed to confirm any causal effects and to define more precisely the role of ATT in patients with IE and elevated cardiovascular risk.

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Publication Details

Journal
Clinical Research in Cardiology
Published
2026-02-09
DOI
https://doi.org/10.1007/s00392-026-02859-w
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Antithrombotic therapy in infective endocarditis: Long-term clinical outcomes of a retrospective cohort study

Samuel Tobias Sossalla, Florian Hitzenbichler, Christian Schach, Felix Schlachetzki et al.
Clinical Research in Cardiology
Infective Endocarditis Diagnosis and Management
article

Antithrombotic therapy in infective endocarditis: Long-term clinical outcomes of a retrospective cohort study

Samuel Tobias Sossalla, Florian Hitzenbichler, Christian Schach, Felix Schlachetzki, Jozef Micek, K Debl, Elias Füssl, Kostiantyn Kozakov, Firat Koyun, Carlotta Posner, Henrik Heuer, Hiba Daas, Lukas Krämer
article en

Abstract

In this retrospective cohort, anticoagulated patients did not show a higher rate of adverse events during hospitalization and had a lower long-term event rate. These findings represent correlations observed in a non-randomized, single-center setting and may partly reflect differences in underlying risk profiles and treatment selection (confounding by indication and residual confounding). Prospective studies are needed to confirm any causal effects and to define more precisely the role of ATT in patients with IE and elevated cardiovascular risk.

Clinical Research in Cardiology
Justus-Liebig-Universität Gießen (DE), University Hospital Regensburg (DE), Kerckhoff Klinik (DE)
Universität Regensburg
Good health and well-being
Openalex Percentile: Top 62%
Infective Endocarditis Diagnosis and Management
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