Development and Validation of a Time‐Dependent Nomogram for Predicting Hematological Toxicity Risk During Linezolid Therapy in Drug‐Resistant Tuberculosis
This nomogram, integrating C<sub>min</sub> with baseline clinical factors, enables early identification of patients with DR-TB at high risk for hematotoxicity and could guide pre-emptive interventions. However, external validation is required to confirm its generalizability before widespread clinical implementation.
Authors
- N Chu
- Zhongquan Liu
- Wenjuan Nie
- Wenjie Qi
- Wenhui Shi
- Yang Yang
- Wenqiang Zhou
- Yu Lu
- Hui Zhu
- Qingfeng Wang
Institutions
- Beijing Chest Hospital (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1002/phar.70109
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00