Transcranial Photobiomodulation in Rett Syndrome: A Mechanistic Review and Therapeutic Hypothesis

Although speculative, this mechanistic convergence supports prioritizing preclinical studies in Mecp2-deficient models and early-phase feasibility trials of tPBM in individuals with RTT.

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Publication Details

Journal
Photobiomodulation Photomedicine and Laser Surgery
Published
2026-02-09
DOI
https://doi.org/10.1177/25785478251415480
Primary Topic
Laser Applications in Dentistry and Medicine
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcranial Photobiomodulation in Rett Syndrome: A Mechanistic Review and Therapeutic Hypothesis

Paolo Cassano, Carlos Alberto Lohmann, Borja Ignacio Ferreras, Fabio Luchese
Photobiomodulation Photomedicine and Laser Surgery
Laser Applications in Dentistry and Medicine
article

Transcranial Photobiomodulation in Rett Syndrome: A Mechanistic Review and Therapeutic Hypothesis

Paolo Cassano, Carlos Alberto Lohmann, Borja Ignacio Ferreras, Fabio Luchese
article en

Abstract

Although speculative, this mechanistic convergence supports prioritizing preclinical studies in Mecp2-deficient models and early-phase feasibility trials of tPBM in individuals with RTT.

Photobiomodulation Photomedicine and Laser Surgery
Harvard University (US), Massachusetts General Hospital (US)
Openalex Percentile: Top 64%
Laser Applications in Dentistry and Medicine
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